| ncRNA name | hsa-miR-22 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell line Y79 |
| Methods | microarray, qRT-PCR, transfection, MTT assay, in-vitro scratch migration assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-22, a tumor-suppressor miRNA was one of the miRNA which was upregulated by curcumin. Transfected miR-22 Y79 cells inhibited the cell proliferation and reduced the migration, and erythoblastic leukemia viral oncogene homolog 3 (Erbb3) was confirmed to be the target gene of miR-22. |
| PubMed ID | 22510010 |
| Year | 2012 |
| Title | Effect of curcumin on miRNA expression in human Y79 retinoblastoma cells. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.